The Network Infrastructure Data Science (NIDS) course presents a data-science framing for conversations about the role of Internet measurement and data science in a range of public policy issues, with an emphasis on cybersecurity. It focuses on the Internet as a data transport service, and vulnerabilities specific to interdomain routing (BGP), naming (Domain Name System), and certificate management. Persistent security challenges at this layer affect every application that operates over the Internet. The course provides a data-oriented background on these critical dimensions of the Internet infrastructure.